Molecular Bases of Human Papillomavirus Pathogenesis in the Development of Cervical Cancer
نویسندگان
چکیده
Adolfo Pedroza-Saavedra1, Tanya Plett-Torres1, Lilia Chihu-Amparán1, Minerva Maldonado-Gama1, Ana M. González-Jaimes1, Fernando Esquivel-Guadarrama2 and Lourdes Gutiérrez-Xicotencatl1 1Department of Epidemiological Interactions, Center of Research on Infectious Diseases, National Institute of Public Health. 2Faculty of Medicine, Autonomous University of Morelos State. 1,2Cuernavaca, Morelos, Mexico
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Exposing the Molecular Screening Method of Indonesian Natural Products Derivate as Drug Candidates for Cervical Cancer
The menace of cervical cancer has reached an alarming rate. There are more than 450.000cases of cervical cancer yearly, with mortality rate of about 50%. This deadly cancer is causedby human papillomavirus (HPV), mainly subtypes 16 and 18. The pharmaceutical industryhas produced drug for combating the virus, known as SAHA (suberoylanilide hydroxamicacid). It inhibits class II HDAC Homo sapiens ...
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